BDBM191369 WO2005082863, Example 8A::example 8A disclosed in WO 2005/082863

SMILES CC(=O)C1=C(C)N(C(=O)N[C@H]1C#N)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=BTAVKKCALHGPKT-LBPRGKRZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191369   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM191369(WO2005082863, Example 8A | example 8A disclosed in...)
Affinity DataIC50:  1.20E+4nMpH: 7.5 T: 2°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C8(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM191369(WO2005082863, Example 8A | example 8A disclosed in...)
Affinity DataIC50:  1.09E+4nMpH: 7.5 T: 2°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM191369(WO2005082863, Example 8A | example 8A disclosed in...)
Affinity DataIC50:  7.30E+4nMpH: 7.5 T: 2°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent