BDBM191630 US9182402, 3

SMILES Brc1cccc(c1)N1C(=O)NC(=O)\C(=C/c2c[nH]c3ccccc23)C1=O

InChI Key InChIKey=IETMBPXNQGYBQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191630   

TargetSerine protease hepsin(Human)
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM191630(US9182402, 3)
Affinity DataIC50: 1.93E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTrypsin(Pig)
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM191630(US9182402, 3)
Affinity DataIC50: 7.63E+3nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetProthrombin(Bovine)
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM191630(US9182402, 3)
Affinity DataIC50: 2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent