BDBM192240 US9187441, KK273

SMILES CC(C)CC(NC(C(=O)NCc1ccccc1)c1c([nH]c2cc(Cl)ccc12)C(O)=O)C(=O)NCCN1CCOCC1

InChI Key InChIKey=CZXLKXIBENLKBB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192240   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM192240(US9187441, KK273)
Affinity DataKi:  400nM ΔG°:  -8.40kcal/molepH: 7.4 T: 2°CAssay Description:All NMR spectra were acquired at 298 K on a Bruker DRX 600 MHz spectrometer equipped with a cryoprobe. Typically, NMR samples contained 0.1-0.2 mM pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent