BDBM192325 US9187462, I-5

SMILES CC(C)Nc1ncc2ccc(cc2n1)C(=O)N[C@H]([C@H]1CCCN1)c1ccc(c(F)c1)C(F)(F)F

InChI Key InChIKey=JYEXVJLIAPTLGM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192325   

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandPNGBDBM192325(US9187462, I-5)
Affinity DataIC50: 2.30nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an N-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent