BDBM19242 (2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(3-fluoro-4-isothiocyanatophenoxy)-2-hydroxy-2-methylpropanamide::arylisothiocyanato derivative, S-26

SMILES C[C@](O)(COc1ccc(N=C=S)c(F)c1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=DZWXQPUTYGLGPD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19242   

TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

LigandPNGBDBM19242((2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(3-fl...)
Affinity DataKi:  6.30nM ΔG°:  -10.4kcal/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2007
Entry Details Article
PubMed