BDBM192451 US9187466, 49::US9687476, 49

SMILES O=c1n(Cc2nnc(Cc3ccccc3Cl)[nH]2)nc(-c2ccc(Cl)cc2)n1C[C@H](O)C(F)(F)F

InChI Key InChIKey=FAWALGPNENMHOB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 192451   

TargetVasopressin V2 receptor(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 192451BDBM192451(US9187466, 49 | US9687476, 49)
Affinity DataIC50: 1.5nMAssay Description:On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent

TargetVasopressin V2 receptor(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 192451BDBM192451(US9187466, 49 | US9687476, 49)
Affinity DataIC50: 1.5nMT: 2°CAssay Description:On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 192451BDBM192451(US9187466, 49 | US9687476, 49)
Affinity DataIC50: 19nMAssay Description:On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent

TargetVasopressin V1a receptor(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 192451BDBM192451(US9187466, 49 | US9687476, 49)
Affinity DataIC50: 19nMT: 2°CAssay Description:On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent