BDBM192582 US9187486, 48
SMILES N[C@H]1C[C@@H](F)CN(C1)c1ccncc1Nc1ncc2ccc(nn12)-c1c(F)cccc1F
InChI Key InChIKey=KYPWRLVQGWQNEA-KGLIPLIRSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 192582
Affinity DataIC50: 0.800nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Affinity DataIC50: 983nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Inhibition of recombinant Pim1 (unknown origin) by electrochemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant Pim2 (unknown origin) by electrochemiluminescence assayMore data for this Ligand-Target Pair