BDBM192586 US9187486, 54
SMILES C[C@@H]1[C@@H](N)CCCN1c1ccncc1Nc1ncc2ccc(nn12)-c1c(F)cccc1F
InChI Key InChIKey=UOMPPOVQMYNXST-KDOFPFPSSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 192586
Affinity DataIC50: 0.100nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0620nMAssay Description:Inhibition of recombinant Pim1 (unknown origin) by electrochemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 221nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.290nMAssay Description:Inhibition of recombinant Pim2 (unknown origin) by electrochemiluminescence assayMore data for this Ligand-Target Pair