BDBM193020 US9193726, 8
SMILES C[C@@H]([C@@H]1CC[C@@H](O1)c1ccc(cc1)C(F)(F)F)N1CCn2c(ccc(-n3cnc(C)c3)c2=O)C1=O
InChI Key InChIKey=CZCJRJMKFMFGOG-WQTXXOFMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 193020
Affinity DataEC50: 14nMAssay Description:Modulation of gamma-secretase in CHO cells expressing human APP assessed as reduction in amyloid beta (1 to 42 residues) production after 24 hrs by E...More data for this Ligand-Target Pair
Affinity DataIC50: 14.3nMT: 37°CAssay Description:The ability of compounds to modulate production of amyloid beta protein
Abeta(1-42) was determined using human WT-APP overexpressing CHO cells.
Cel...More data for this Ligand-Target Pair