BDBM193030 (S)-N-((R or S)-(3- chloro-4- fluorophenyl)(4- (difluoromethoxy) phenyl)methyl)-2- oxooxazolidine-5- carboxamide::US12516046, Example 48B

SMILES O=C3NC[C@@H](C(=O)NC(c1ccc(OC(F)F)cc1)c2ccc(F)c(Cl)c2)O3

InChI Key InChIKey=RRZHAGXRXUGXOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193030   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 193030BDBM193030((S)-N-((R or S)-(3- chloro-4- fluorophenyl)(4- (di...)
Affinity DataIC50: 6.80nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2026
Entry Details
US Patent