BDBM193044 (S)—N—((R)-(4-chloro-2-methoxyphenyl)(4-fluorophenyl)methyl)-2-oxooxazolidine-5-carboxamide and (S)—N—((S)-(4-chloro-2-methoxyphenyl)(4-fluorophenyl)methyl)-2-oxooxazolidine-5-carboxamide::US12516046, Example 55B

SMILES COc1cc(Cl)ccc1C(NC(=O)[C@@H]2CNC(=O)O2)c3ccc(F)cc3

InChI Key InChIKey=OUAVFEDOXNXZAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193044   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 193044BDBM193044((S)—N—((R)-(4-chloro-2-methoxyphenyl)(4-fluorophen...)
Affinity DataIC50: 4.70nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2026
Entry Details
US Patent