BDBM193061 (S)-N-((R or S)-(5- chloro-6- (trifluoromethyl) pyridin-2-yl)(4,4- difluoro- cyclohexyl)methyl)- 2-oxooxazolidine-5- carboxamide::US12516046, Example 63A

SMILES Cc3nc(C(NC(=O)[C@@H]1CNC(=O)O1)C2CCC(F)(F)CC2)ccc3Cl

InChI Key InChIKey=DZWWZBJXRSLXIJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193061   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 193061BDBM193061((S)-N-((R or S)-(5- chloro-6- (trifluoromethyl) py...)
Affinity DataIC50: 12nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2026
Entry Details
US Patent