BDBM193070 (S)—N—((R or S)-(3-chloro-2,4-difluorophenyl)((trans)-3-(trifluoromethyl)cyclobutyl)methyl)-2-oxooxazolidine-5-carboxamide::US12516046, Example 70

SMILES C[C@@H]3C[C@@H](C(NC(=O)[C@@H]1CNC(=O)O1)c2ccc(F)c(Cl)c2F)C3

InChI Key InChIKey=FQTUFQGZTOKOID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193070   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 193070BDBM193070((S)—N—((R or S)-(3-chloro-2,4-difluorophenyl)((tra...)
Affinity DataIC50: 5.40nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2026
Entry Details
US Patent