BDBM193071 (S)-N-((R or S)-(3- chloro-2,4- difluorophenyl)(2- (2,2,2- trifluoroethoxy)thiazol- 5-yl)methyl)-2- oxooxazolidine-5- carboxamide::US12516046, Example 71A

SMILES CCOc3ncc(C(NC(=O)[C@@H]1CNC(=O)O1)c2ccc(F)c(Cl)c2F)s3

InChI Key InChIKey=NNEYYGOJDKENAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193071   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 193071BDBM193071((S)-N-((R or S)-(3- chloro-2,4- difluorophenyl)(2-...)
Affinity DataIC50: 3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2026
Entry Details
US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 193071BDBM193071((S)-N-((R or S)-(3- chloro-2,4- difluorophenyl)(2-...)
Affinity DataIC50: 11nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2026
Entry Details
US Patent