BDBM193083 3-((4-(1'-(5-((1R,3R)-2-(2,2-difluoroethyl)- 3-methyl-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-yl)pyrimidin-2-yl)- [1,4'-bipiperidin]-4-yl)-3- fluorophenyl)amino)piperidine-2,6-dione::US20260007681, Compound A3

SMILES C[C@@H]8Cc1c([nH]c2ccccc12)[C@@H](c7cnc(N6CCC(N5CCC(c4ccc(NC3CCC(=O)NC3=O)cc4F)CC5)CC6)nc7)N8CC(F)F

InChI Key InChIKey=MHLAGDGKSQVFQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193083   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 193083BDBM193083(3-((4-(1'-(5-((1R,3R)-2-(2,2-difluoroethyl)- 3-met...)
Affinity DataIC50: 275nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent