BDBM193819 US9670209, Compound 321 1-((R)-3-(3-(cyclopropylmethoxy)-8-aza-bicyclo[3.2.1]octan-8-yl)-2-methylpropyl)-5-methyl-1H-indazole

SMILES C[C@H](CN1[C@H]2CC[C@@H]1C[C@@H](C2)OCC1CC1)Cn1ncc2cc(C)ccc12

InChI Key InChIKey=JRJZHTCPZCYIBW-GFRNBQLOSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193819   

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193819(US9670209, Compound 321 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  7.90nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193819(US9670209, Compound 321 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  13nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent