BDBM195030 US9206198, 53A

SMILES C[C@@H]([C@H](O)c1ccc2C(=O)OCc2c1C)N1CCC2(CCN(C2=O)C2=C(C)C(=O)OC2)CC1

InChI Key InChIKey=TYEGYOCBCGKMJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195030   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Universidade Federal De Minas Gerais

Curated by ChEMBL
LigandPNGBDBM195030(US9206198, 53A)
Affinity DataIC50: 10nMAssay Description:Inhibition of ROMK (unknown origin) by Thallium Efflux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Universidade Federal De Minas Gerais

Curated by ChEMBL
LigandPNGBDBM195030(US9206198, 53A)
Affinity DataIC50: 10nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent