BDBM195045 US9212153, 100,Ex. 66

SMILES CN1OC2(N=C1N)c1cc(ccc1CC21CCC(CC1)OC(F)F)-c1cccc(c1)[N+]#[C-]

InChI Key InChIKey=GRSIXJXGUIPXKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 195045   

TargetBeta-secretase 1 [1-458](Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM195045(US9212153, 100,Ex. 66)
Affinity DataIC50:  4.70nMpH: 4.5 T: 25°CAssay Description:Inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE activity using commercially available substrate HiLyte Fluor 488...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent