BDBM195522 US9212153, 335,Ex. 282
SMILES COC1CCC2(Cc3ccc(cc3[C@]22N=C(N)N(C[C@H]3CCCO3)C2=O)C#CC2CC2)CC1
InChI Key InChIKey=BHUFUPBWYHSWOM-UZLQEEKBSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 195522
Affinity DataIC50: 2.20nMpH: 4.4Assay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair