BDBM195576 cis-1-(3-(4-(2-morpholinopyrimidin-5-yl)phenyl)-1H-1,2,4-triazole-1-carbonyl)-2-phenylpiperidine-4-carboxylic acid (7)

SMILES OC(=O)C1CCN(C(C1)c1ccccc1)C(=O)n1cnc(n1)-c1ccc(cc1)-c1cnc(nc1)N1CCOCC1

InChI Key InChIKey=PYMNLIKHRFXDQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195576   

TargetLiver carboxylesterase 1(Human)
Pfizer

LigandPNGBDBM195576(cis-1-(3-(4-(2-morpholinopyrimidin-5-yl)phenyl)-1H...)
Affinity DataIC50:  3.60E+4nMpH: 7.5Assay Description:For determination of IC50 values for CES1 inhibitors, the reactions were carried out in 1.5 mL microcentrifuge tubes in a total reaction volume of 25...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM195576(cis-1-(3-(4-(2-morpholinopyrimidin-5-yl)phenyl)-1H...)
Affinity DataIC50:  710nMpH: 7.5Assay Description:For determination of IC50 values for LYPLAL1 inhibitors, the reactions were carried out in 1.5 mL microcentrifuge tubes in a total reaction volume of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed