BDBM195645 US9206173, 2407

SMILES CC#CCn1c(N[C@@H](C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1ccc(cc1)C#N

InChI Key InChIKey=BVHLHXNYDYAUQE-SFHVURJKSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195645   

TargetProlactin-releasing peptide receptor(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM195645(US9206173, 2407)
Affinity DataKi:  8nM ΔG°:  -11.0kcal/molepH: 7.4 T: 25°CAssay Description:Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetProlactin-releasing peptide receptor(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM195645(US9206173, 2407)
Affinity DataIC50:  207nMpH: 7.4 T: 25°CAssay Description:HEK293 cells expressing human GPR10 were maintained in Dulbecco's Modified Eagles' medium supplemented with 10% fetal bovine serum, 1% penici...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent