BDBM19629 (2S)-2-(1,3-benzoxazol-2-ylamino)-3-cyclohexyl-N-[2-(5-fluoro-2,3-dihydro-1H-indol-1-yl)ethyl]propanamide::Heterocyclic arylaminoethyl amide, 13a

SMILES Fc1ccc2N(CCNC(=O)[C@H](CC3CCCCC3)Nc3nc4ccccc4o3)CCc2c1

InChI Key InChIKey=BKAMPSRSQOUJKP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19629   

TargetCathepsin S(Human)
Gnf

LigandPNGBDBM19629((2S)-2-(1,3-benzoxazol-2-ylamino)-3-cyclohexyl-N-[...)
Affinity DataKi:  222nM ΔG°:  -9.44kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandPNGBDBM19629((2S)-2-(1,3-benzoxazol-2-ylamino)-3-cyclohexyl-N-[...)
Affinity DataKi: >1.00E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandPNGBDBM19629((2S)-2-(1,3-benzoxazol-2-ylamino)-3-cyclohexyl-N-[...)
Affinity DataKi: >3.00E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed