BDBM197548 US9216968, 148::US9732066, 148

SMILES Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2ccccc2C(F)(F)F)cc2[nH]c(nc12)N1CC(O)C1

InChI Key InChIKey=RJZHNPHIYZEDNA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197548   

TargetProstaglandin E synthase(Human)
Nippon Shinyaku

US Patent
LigandPNGBDBM197548(US9216968, 148 | US9732066, 148)
Affinity DataIC50:  1.90nMAssay Description:mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetProstaglandin E synthase(Human)
Nippon Shinyaku

US Patent
LigandPNGBDBM197548(US9216968, 148 | US9732066, 148)
Affinity DataIC50:  1.90nMAssay Description:mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent