BDBM197685 US9216981, 13

SMILES O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F)c1ccc(F)cc1C(F)(F)F

InChI Key InChIKey=MODKADBEDFUKGW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197685   

TargetSerine/threonine-protein kinase B-raf(Human)
Medpacto

US Patent
LigandChemical structure of BindingDB Monomer ID 197685BDBM197685(US9216981, 13)
Affinity DataEC50:  150nMT: 2°CAssay Description:To check the B-Raf cell activity inhibitory capability of the compounds of the present invention, the following experiments were conducted in A375P c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Medpacto

US Patent
LigandChemical structure of BindingDB Monomer ID 197685BDBM197685(US9216981, 13)
Affinity DataIC50: 420nMpH: 7.2 T: 2°CAssay Description:To check the B-Raf kinase inhibitory activity of the compounds of the present invention, the following experiments were conducted.(1) Serial Signalin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent