BDBM197793 BDBM197870::US9216988, 15

SMILES CC(c1ccccc1)S(=O)(=O)N(Cc1ccc(cc1F)N1CCN(CC1)C(C)=O)CC(F)(F)F

InChI Key InChIKey=NYABPKUHLNSIOT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 197793   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM197793(US9216988, 15 | BDBM197870)
Affinity DataIC50: 10nMpH: 7.4Assay Description:On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM197793(US9216988, 15 | BDBM197870)
Affinity DataIC50: 11nMpH: 7.4Assay Description:On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM197793(US9216988, 15 | BDBM197870)
Affinity DataIC50: 120nMpH: 7.4Assay Description:On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent