BDBM19787 (2S)-3,3-dimethyl-1-[3-(trifluoromethyl)-1H-pyrazol-1-yl]butan-2-yl N-[(2S)-3-oxo-4-(pyridine-2-sulfonamido)butan-2-yl]carbamate::ketone analog, 3d

SMILES C[C@H](NC(=O)O[C@H](Cn1ccc(n1)C(F)(F)F)C(C)(C)C)C(=O)CNS(=O)(=O)c1ccccn1

InChI Key InChIKey=LHFHMLNAFKHCBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19787   

TargetCathepsin K(Human)
Gsk

LigandPNGBDBM19787((2S)-3,3-dimethyl-1-[3-(trifluoromethyl)-1H-pyrazo...)
Affinity DataIC50: 300nMpH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
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Date in BDB:
1/5/2008
Entry Details Article
PubMed