BDBM198878 BDBM198879::US9221797, 62

SMILES CC1(C)CC=C(c2cc(C(C)(C)N3CCN(CCO)CC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1

InChI Key InChIKey=AWROSJBGNHPYIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 198878   

TargetMacrophage colony-stimulating factor 1 receptor [555-568](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 198878BDBM198878(BDBM198879 | US9221797, 62)
Affinity DataIC50: 0.690nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor [555-568](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 198878BDBM198878(BDBM198879 | US9221797, 62)
Affinity DataIC50: 0.880nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent