BDBM198882 US9221797, 67

SMILES C=C(CNCCOC)c1ccc(NC(=O)c2nc(C#N)c[nH]2)c(C2=CCCCC2)c1

InChI Key InChIKey=GFHVNJTZYHPCTM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198882   

TargetMacrophage colony-stimulating factor 1 receptor [555-568](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 198882BDBM198882(US9221797, 67)
Affinity DataIC50: 1.30nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent