BDBM199420 US9221831, 86
SMILES CO[C@]12CC[C@@]3(C[C@@H]1COC(=O)[C@H](C)N)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45
InChI Key InChIKey=UMJCUZCZSKADAB-ZLQRJZPTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 199420
Affinity DataKi: 0.140nMpH: 7.4Assay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nM ΔG°: -13.1kcal/molepH: 7.4 T: 50°CAssay Description:Radioligand dose-displacement binding assays for t-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...More data for this Ligand-Target Pair
Affinity DataEC50: 2.59nMpH: 7.4 T: 25°CAssay Description:Functional [35S]GTPgammaS binding assays were conducted as follows. κ
opioid receptor membrane solution was prepared by sequentially adding
final ...More data for this Ligand-Target Pair