BDBM19945 3-arylquinazolinone, 1aal::7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-3,4-dihydroquinazoline-5-carbonitrile

SMILES Oc1ccc(cc1)-n1cnc2cc(O)cc(C#N)c2c1=O

InChI Key InChIKey=XRRKCZCIDGLMFZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19945   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM19945(7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-3,4-dihydroqui...)
Affinity DataIC50: 7.37E+4nM EC50:  7.58E+3nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM19945(7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-3,4-dihydroqui...)
Affinity DataAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed