BDBM200528 US9670231, 1.43

SMILES CC(C)(C#N)c1cccc(c1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12

InChI Key InChIKey=LGMCTZVEXBYIIM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 200528   

LigandPNGBDBM200528(US9670231, 1.43)
Affinity DataIC50: 0.340nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Beigene

US Patent
LigandPNGBDBM200528(US9670231, 1.43)
Affinity DataIC50: 4.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R](Human)
Beigene

US Patent
LigandPNGBDBM200528(US9670231, 1.43)
Affinity DataIC50: 11nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Beigene

US Patent
LigandPNGBDBM200528(US9670231, 1.43)
Affinity DataIC50: 13nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

LigandPNGBDBM200528(US9670231, 1.43)
Affinity DataIC50: 38nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent