BDBM202225 US9233983, R-4

SMILES CN1CC(N2CC=C(c3cc4c(-c5cccc(N6CCOc7cc(C8CC8)cc(F)c7C6=O)c5CO)ccnc4[nH]3)CC2)C1

InChI Key InChIKey=AQYSJGQDGZJWHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202225   

TargetTyrosine-protein kinase BTK(Human)
Advinus Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 202225BDBM202225(US9233983, R-4)
Affinity DataIC50: 1.60nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent