BDBM203300 US10227340, Example 129::US9242975, 129

SMILES CC(C)Nc1cc(Nc2ccc3ncsc3c2)ncc1-c1nnc(o1)N1CCN(CCO)CC1

InChI Key InChIKey=VGIFSOHWEZBPTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 203300   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM203300(US10227340, Example 129 | US9242975, 129)
Affinity DataIC50:  25.4nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM203300(US10227340, Example 129 | US9242975, 129)
Affinity DataIC50:  25.4nMpH: 7.2 T: 25°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substrates...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent