BDBM203460 US9242995, 1-8

SMILES COc1ccc(CNC(=O)c2cc(nc3onc(-c4ccccc4)c23)-c2cncc(Br)c2)nc1OC

InChI Key InChIKey=QFLUOTGCQNIZIR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 203460   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203460(US9242995, 1-8)
Affinity DataKi:  3.80nM ΔG°:  -11.9kcal/moleT: 2°CAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
US Patent