BDBM203461 US9242995, 1-12

SMILES COc1ccc(CNC(=O)c2cc(nc3onc(-c4ccccc4)c23)-c2cncc(C)c2)cc1OC

InChI Key InChIKey=VJSSPVVNPLDNEH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 203461   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203461(US9242995, 1-12)
Affinity DataKi:  10.8nM ΔG°:  -11.3kcal/moleT: 2°CAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
US Patent