BDBM204831 US9242977, 34
SMILES CCNc1ncc(s1)-c1ccc(Oc2ccc(NC(=O)Nc3cc(cnc3-c3ccc(C)c(C)c3)C(F)(F)F)cn2)cc1
InChI Key InChIKey=KPFPNNCNIXMYCQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 204831
TargetIsoform TrkA-I of High affinity nerve growth factor receptor (TrkAI)(Human)
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataIC50: 6nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
TargetIsoform TrkA-I of High affinity nerve growth factor receptor (TrkAI)(Human)
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataIC50: 180nMpH: 7.5Assay Description:TrkA-inhibiting activity was measured according to the following method using LanthaScreen kinase assay reagents (Invitrogen; Fluorescein-Poly GT, La...More data for this Ligand-Target Pair