BDBM204839 US9242977, 66-27
SMILES COC(=O)c1cccc(c1)-n1nc(cc1NC(=O)Nc1cnc(Oc2ccc(cc2)-c2cnc(s2)N2CCCC2=O)nc1)C(C)(C)C
InChI Key InChIKey=ODGQYNDBTMEAKZ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 204839
TargetIsoform TrkA-I of High affinity nerve growth factor receptor (TrkAI)(Human)
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataIC50: 10nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
TargetIsoform TrkA-I of High affinity nerve growth factor receptor (TrkAI)(Human)
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataIC50: 130nMpH: 7.5Assay Description:TrkA-inhibiting activity was measured according to the following method using LanthaScreen kinase assay reagents (Invitrogen; Fluorescein-Poly GT, La...More data for this Ligand-Target Pair