BDBM204842 US9242977, 71

SMILES Cn1ncc2cc(ccc12)-n1nc(cc1NC(=O)Nc1cnc(Oc2ccc(cc2)-c2cnc(s2)N2CCCC2=O)nc1)C(C)(C)C

InChI Key InChIKey=DUBXAXVVOSXJND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204842   

TargetIsoform TrkA-I of High affinity nerve growth factor receptor (TrkAI)(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM204842(US9242977, 71)
Affinity DataIC50:  2nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform TrkA-I of High affinity nerve growth factor receptor (TrkAI)(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM204842(US9242977, 71)
Affinity DataIC50:  30nMpH: 7.5Assay Description:TrkA-inhibiting activity was measured according to the following method using LanthaScreen kinase assay reagents (Invitrogen; Fluorescein-Poly GT, La...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent