BDBM204844 US9242977, 72-3

SMILES Cc1ccccc1-n1nc(cc1NC(=O)Nc1cnc(Oc2ccc(cc2)-c2cnc(s2)N2CCCC2=O)nc1)C(C)(F)F

InChI Key InChIKey=XWLGFOFXYSCKFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204844   

LigandPNGBDBM204844(US9242977, 72-3)
Affinity DataIC50: 18nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details
US Patent

LigandPNGBDBM204844(US9242977, 72-3)
Affinity DataIC50: 60nMpH: 7.5Assay Description:TrkA-inhibiting activity was measured according to the following method using LanthaScreen kinase assay reagents (Invitrogen; Fluorescein-Poly GT, La...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details
US Patent