BDBM204862 EA2/MRS5811::US9227979, 11

SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc(CC(O)=O)cc1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=QOVZGPDUOLJANP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 204862   

TargetAdenosine receptor A3(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 204862BDBM204862(US9227979, 11 | EA2/MRS5811)
Affinity DataKi:  128nMAssay Description:Radioligand binding assays at hA1, hA2A, and hA3ARs were performed according to the procedures described in Gao, Z. G., et al., Biochem Pharmacol. 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details
US Patent

TargetAdenosine receptor A3(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 204862BDBM204862(US9227979, 11 | EA2/MRS5811)
Affinity DataKi:  128nMAssay Description:Displacement of [125I]AB-MEC from recombinant human A3R expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Trieste

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 204862BDBM204862(US9227979, 11 | EA2/MRS5811)
Affinity DataKi:  1.01E+3nMAssay Description:Displacement of [3H]CGS21680 from recombinant human A2AAR expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Trieste

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 204862BDBM204862(US9227979, 11 | EA2/MRS5811)
Affinity DataKi:  1.01E+3nMAssay Description:Radioligand binding assays at hA1, hA2A, and hA3ARs were performed according to the procedures described in Gao, Z. G., et al., Biochem Pharmacol. 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details
US Patent