BDBM205440 6S+IBET-PEG4 (21)

SMILES COc1cc2c(cc1-c1c(C)noc1C)ncc1c2n([C@H](C)c2ccccn2)c(=O)n1CC(=O)NCCOCCOCCOCCOCCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2c(sc(C)c2C)-n2c(C)nnc21

InChI Key InChIKey=ZJKGEINLDGYOLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 205440   

TargetBromodomain testis-specific protein [21-137](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205440BDBM205440(6S+IBET-PEG4 (21))
Affinity DataIC50: 6.20nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Dana-Farber Cancer Institute

LigandChemical structure of BindingDB Monomer ID 205440BDBM205440(6S+IBET-PEG4 (21))
Affinity DataIC50: 29.5nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed