BDBM20575 N-[4-({6-[4-(diphenylmethyl)piperazin-1-yl]pyrimidin-4-yl}oxy)-1,3-benzothiazol-2-yl]acetamide::Piperazinylpyrimidine analogue, 16k

SMILES CC(=O)Nc1nc2c(Oc3cc(ncn3)N3CCN(CC3)C(c3ccccc3)c3ccccc3)cccc2s1

InChI Key InChIKey=CQFSJGBTAKTFEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20575   

LigandPNGBDBM20575(N-[4-({6-[4-(diphenylmethyl)piperazin-1-yl]pyrimid...)
Affinity DataIC50:  20nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20575(N-[4-({6-[4-(diphenylmethyl)piperazin-1-yl]pyrimid...)
Affinity DataIC50:  1.40E+3nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed