BDBM20575 N-[4-({6-[4-(diphenylmethyl)piperazin-1-yl]pyrimidin-4-yl}oxy)-1,3-benzothiazol-2-yl]acetamide::Piperazinylpyrimidine analogue, 16k
SMILES CC(=O)Nc1nc2c(Oc3cc(ncn3)N3CCN(CC3)C(c3ccccc3)c3ccccc3)cccc2s1
InChI Key InChIKey=CQFSJGBTAKTFEK-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 20575
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Amgen
Amgen
Affinity DataIC50: 20nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Amgen
Amgen
Affinity DataIC50: 1.40E+3nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair