BDBM20577 N-{4-[(6-{4-[(1S)-1-(2-fluorophenyl)ethyl]piperazin-1-yl}pyrimidin-4-yl)oxy]-1,3-benzothiazol-2-yl}acetamide::Piperazinylpyrimidine analogue, 17b

SMILES CC(N1CCN(CC1)c1cc(Oc2cccc3sc(NC(C)=O)nc23)ncn1)c1ccccc1F

InChI Key InChIKey=UXOPJAPVVDVYHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20577   

LigandPNGBDBM20577(N-{4-[(6-{4-[(1S)-1-(2-fluorophenyl)ethyl]piperazi...)
Affinity DataIC50: 2.5nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20577(N-{4-[(6-{4-[(1S)-1-(2-fluorophenyl)ethyl]piperazi...)
Affinity DataIC50: 2.70nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed