BDBM206000 3-((S)-7-((7-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-7-azaspiro[3.5]nonan-2-yl)methyl)-1- oxo-1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A6

SMILES C[C@@H]%11Cc1c([nH]c2ccccc12)[C@@H](c%10cnc(N3CCC9(CC3)CC(CN8CCN7c6ccc5C(=O)N(C4CCC(=O)NC4=O)Cc5c6OC[C@@H]7C8)C9)nc%10)N%11CC(F)F

InChI Key InChIKey=CJGXXJJNOAUSEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206000   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206000BDBM206000(3-((S)-7-((7-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-...)
Affinity DataIC50: 50nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent