BDBM206012 6-(1-((1R,3r)-3-((5-((1R,3R)-2- (2,2-difluoroethyl)-3-methyl- 2,3,4,9-tetrahydro-1H-pyrido[3,4- b]indol-1-yl)pyrimidin-2- yl)oxy)cyclobutane-1- carbonyl)piperidin-4-yl)-2-(2,6- dioxopiperidin-3-yl)-6,7- dihydropyrrolo[3,4-f]isoindole- 1,3(2H,5H)-dione::US20260007681, Compound A18

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2cnc(O[C@H]3C[C@H](C(=O)N4CCC(N5Cc6cc7c(cc6C5)C(=O)N(C5CCC(=O)NC5=O)C7=O)CC4)C3)nc2)N1CC(F)F

InChI Key InChIKey=FHAJPMJPKQQHFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206012   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206012BDBM206012(6-(1-((1R,3r)-3-((5-((1R,3R)-2- (2,2-difluoroethyl...)
Affinity DataIC50: 275nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent