BDBM206016 3-((S)-3-(((R)-4-(5- ((1R,3R)-2-(2-fluoro-2- methylpropyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1- yl)pyrimidin-2-yl)morpholin-2-yl) methyl)-8-oxo-1,2,3,4,4a,5,8,10- octahydro-9H-pyrazino[1',2':4,5][1,4] oxazino[2,3-f]isoindol-9-yl)piperidine- 2,6-dione::US20260007681, Compound A22

SMILES C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N8CCO[C@H](CN7CCN6c5cc4CN(C3CCC(=O)NC3=O)C(=O)c4cc5OC[C@@H]6C7)C8)nc9)N%10CC(C)(C)F

InChI Key InChIKey=WRXACWYBFQONAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206016   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206016BDBM206016(3-((S)-3-(((R)-4-(5- ((1R,3R)-2-(2-fluoro-2- methy...)
Affinity DataIC50: 275nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent