BDBM206024 (S)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)- N-((S)-2,6-dioxopiperidin-3-yl)-9-fluoro- 1,2,3,4,4a,5- hexahydrobenzo[b]pyrazino[1,2- d][1,4]oxazine-8-carboxamide::US20260007681, Compound A30

SMILES COc6cc(N5CCC(CN4CCN3c2cc(F)c(C(=O)N[C@H]1CCC(=O)NC1=O)cc2OC[C@@H]3C4)CC5)ccc6[C@@H]9c8[nH]c7ccccc7c8C[C@@H](C)N9CC(F)F

InChI Key InChIKey=XYUGKDSHQAEBLF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206024   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206024BDBM206024((S)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-met...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent