BDBM206026 3-(5-(1-((7-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyrimidin-2- yl)-7-azaspiro[3.5]nonan-2- yl)methyl)piperidin-4-yl)-3-methyl-2-oxo- 2,3-dihydro-1H-benzo[d]imidazol-1- yl)piperidine-2,6-dione::US20260007681, Compound A32

SMILES C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N3CCC8(CC3)CC(CN7CCC(c4ccc5c(c4)n(C)c(=O)n5C6CCC(=O)NC6=O)CC7)C8)nc9)N%10CC(F)F

InChI Key InChIKey=KIRYOWGBLGLINP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206026   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206026BDBM206026(3-(5-(1-((7-(5-((1R,3R)-2-(2,2- difluoroethyl)-3-m...)
Affinity DataIC50: 275nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent