BDBM206028 (S)-3-((4-(1-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4- yl)methyl)piperidin-4-yl)-3- fluorophenyl)amino)piperidine-2,6- dione::US20260007681, Compound A34

SMILES COc5cc(N4CCC(CN3CCC(c2ccc(N[C@H]1CCC(=O)NC1=O)cc2F)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F

InChI Key InChIKey=HQOQXUHKLUVJIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206028   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206028BDBM206028((S)-3-((4-(1-((1-(4-((1R,3R)-2-(2,2- difluoroethyl...)
Affinity DataIC50: 50nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent