BDBM206038 (R)-3-((S)-3-((1-(4-((1S,3S)-2-(2,2- difluoroethyl)-3-methyl-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A44

SMILES COc7cc(N6CCC(CN5CCN4c3cc2CN([C@@H]1CCC(=O)NC1=O)C(=O)c2cc3OC[C@@H]4C5)CC6)ccc7[C@H]%10c9[nH]c8ccccc8c9C[C@H](C)N%10CC(F)F

InChI Key InChIKey=ZHTPIQFRAPUAAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206038   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206038BDBM206038((R)-3-((S)-3-((1-(4-((1S,3S)-2-(2,2- difluoroethyl...)
Affinity DataIC50: 275nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent